At the Institute for Wildlife Disease Research (AIWDR) in the United Republic of Tanzania, Veterinarians Play a Vital and Growing Role in Wildlife Health Research and Conservation

Authors

  • Mahadhi Kilian Ndembo Department of Wildlife Pathobiology and Conservation Medicine, African Institute for Wildlife Disease Research (AIWDR), Arusha, United Republic of Tanzania Author

DOI:

https://doi.org/10.64229/ejbvqp12

Keywords:

Veterinary Medicine, Wildlife Health, One Health, Disease Ecology, Conservation Biology, Wildlife Diagnostics, Zoonotic Diseases, Epidemiological Modeling, Chemical Immobilization, Wildlife Rehabilitation

Abstract

The confluence of veterinary medicine and wildlife health research represents a dynamic and critically important frontier in conservation science, public health, and ecosystem management. The historical paradigm, which viewed wildlife diseases as density-dependent regulators or incidental phenomena, has been fundamentally overturned by a series of epizootics with catastrophic conservation impacts. The emergence of pathogens like the canine distemper virus in Serengeti lions, the chytrid fungus driving global amphibian declines, and white-nose syndrome decimating Nearctic bat populations, has unequivocally demonstrated that disease can be a primary driver of biodiversity loss. This paradigm shift has positioned veterinary medicine as an indispensable discipline, providing a rigorous, clinical, and population-level framework for investigating and mitigating health threats to wildlife. This article provides a comprehensive synthesis of the integral and multifaceted contributions of veterinary science to wildlife health. We delve into the sophisticated diagnostic toolkit-from field necropsy to advanced genomic sequencing-employed to unravel complex disease aetiologies. We explore the technical challenges and innovations in wildlife immobilization, clinical care, and rehabilitation, emphasizing their role in the conservation of endangered species. Furthermore, we examine the application of veterinary epidemiological principles in modeling disease dynamics and the pivotal function of wildlife health surveillance within the integrative "One Health" framework. Through detailed case studies on avian influenza and chytridiomycosis, and a discussion of emerging challenges like climate change, we argue that the integration of veterinary medicine is not merely additive but transformative. It provides the essential capabilities to diagnose, understand, and combat health threats, thereby securing a future for global biodiversity in an increasingly anthropogenic world. The continued and deepened collaboration between veterinarians, ecologists, wildlife managers, and public health experts is no longer optional but fundamental to effective conservation.

References

[1]Aguirre, AA., & Tabor, G. M. (2004). Introduction: Marine vertebrates as sentinels of marine ecosystem health. EcoHealth, 1: 236-238.

[2]Barnosky, A. D., Matzke, N., Tomiya, S., Wogan, G. O. U., Swartz, B., Quental, T. B., Marshall, C., McGuire, J. L., Lindsey, E. L., Maguire, K. C., Mersey, B., & Ferrer, E. A. (2011). Has the Earth's sixth mass extinction already arrived? Nature, 471, 51-57.

[3]Chen, H., Adam, A., Cheng, Y., Tang, S., Hartung, J., & Bao, E. (2015). Localization and expression of heat shock protein 70 with rat myocardial cell damage induced by heat stress in vitro and in vivo. Molecular Medicine Reports, 11, 2276-2284. https://doi.org/10.3892/mmr.2014.2986

[4]Developmental changes in the role of gonadotropin-inhibitory hormone (GnIH) and its receptors in the reproductive axis of male Xiaomeishan pigs https://doi.org/10.1016/j.anireprosci.2015.01.004

[5]Xu, T., Tao, H., Chang, G. et al. Lipopolysaccharide derived from the rumen down-regulates stearoyl-CoA desaturase 1 expression and alters fatty acid composition in the liver of dairy cows fed a high-concentrate diet. BMC Vet Res 11, 52 (2015). https://doi.org/10.1186/s12917-015-0360-6

[6]Qin T, Yin Y, Huang L, Yu Q, Yang Q. 2015. H9N2 Influenza Whole Inactivated Virus Combined with Polyethyleneimine Strongly Enhances Mucosal and Systemic Immunity after Intranasal Immunization in Mice. Clin Vaccine Immunol 22:.https://doi.org/10.1128/CVI.00778-14

[7]Anderson, R. C., Cookson, A. L., McNabb, W. C., Park, Z., McCann, M. J., Kelly, W. J., et al. (2010). Lactobacillus plantarum MB452 enhances the function of the intestinal barrier by increasing the expression levels of genes involved in tight junction formation. BMC Microbiology 10:316. doi: 10.1186/1471-2180-10-316

[8]X.L. Wang, J. Zhou, M.L. Lu, S.P. Zhao, W.J. Li, G.B. Quan, B. Xue, Mucosal barrier function and microbial community of small intestines in sheep in response to dietary energy concentrations, animal, 10.1016/j.animal.2025.101550, 19, 7, (101550), (2025).

[9]L. Berger, R. Speare, P. Daszak, D.E. Green, A.A. Cunningham, C.L. Goggin, R. Slocombe, M.A. Ragan, A.D. Hyatt, K.R. McDonald, H.B. Hines, K.R. Lips, G. Marantelli, and H. Parkes, Chytridiomycosis causes mortality and associated population declines in Australian and Central American rainforest amphibians, Proceedings of the National Academy of Sciences of the United States of America 95 (15) 9031-9036, https://doi.org/10.1073/pnas.95.15.9031 (1998).

[10]Peter Daszak et al., Emerging Infectious Diseases of Wildlife: Threats to Biodiversity and Human Health. Science 287, 443-449 (2000). DOI: 10.1126/science.287.5452.443

[11]Gibson PR. Increased gut permeability in Crohn’s disease: is TNF the link? Gut (2004) 53(12):1724-5. doi: 10.1136/gut.2004.047092

[12]Ge XT, Feng ZG, Xu TT, Wu BB, Chen HJ, Xu FL, et al. A novel imidazopyridine derivative, X22, attenuates sepsis-induced lung and liver injury by inhibiting the inflammatory response in vitro and in vivo. Drug Des Dev Ther (2016) 10:1947-59. doi: 10.2147/Dddt.S101449

[13]Wang S, Bao Y, Meng Q, Xia Y, Zhao Y, Wang Y, et al. (2015) IbeR Facilitates Stress-Resistance, Invasion and Pathogenicity of Avian Pathogenic Escherichia coli. PLoS ONE 10(3): e0119698. https://doi.org/10.1371/journal.pone.0119698

[14]Liu C, Chen J, Li E, Fan Q, Wang D, Zhang C, et al. (2015) Solomonseal Polysaccharide and Sulfated Codonopsis pilosula Polysaccharide Synergistically Resist Newcastle Disease Virus. PLoS ONE 10(2): e0117916. https://doi.org/10.1371/journal.pone.0117916

[15]Chen, X., Shi, X., Gan, F. et al. Glutamine starvation enhances PCV2 replication via the phosphorylation of p38 MAPK, as promoted by reducing glutathione levels. Vet Res 46, 32 (2015). https://doi.org/10.1186/s13567-015-0168-1

[16]Xie, X., Lin, Y., Pang, M. et al. Monoclonal antibody specific to HA2 glycopeptide protects mice from H3N2 influenza virus infection. Vet Res 46, 33 (2015). https://doi.org/10.1186/s13567-015-0146-7

[17]Haydon, D., Randall, D., Matthews, L. et al. Low-coverage vaccination strategies for the conservation of endangered species. Nature 443, 692-695 (2006). https://doi.org/10.1038/nature05177

Downloads

Published

2025-11-10

Issue

Section

Articles